4321 PERSONALIZATION OF T CELL PRODUCTION FOR CELLULAR IMMUNOTHERAPY

OBJECTIVES/GOALS: Utilize polymer-based fiber scaffolds and machine learning methods applied to patient biomarker data to enhance and personalize T cell expansion and production 2 Way 5.25" for T cell therapy in chronic lymphocytic leukemia.METHODS/STUDY POPULATION: Scaffolds are 1) generated from a co-polymer blend of PDMS and PCL with controlled

Oxidative stress plays a pivotal role in the pathogenesis of atherosclerosis and coronary artery disease (CAD), with both beneficial and detrimental effects on cardiovascular health.On one hand, the excessive production of reactive oxygen species (ROS) contributes 2 Way 5.25" to endothelial dysfunction, inflammation, and vascular remodeling, which